Genotyping Error Detection in Samples of Unrelated Individuals without Replicate Genotyping

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Genotyping error detection in samples of unrelated individuals without replicate genotyping.

OBJECTIVE Identifying genotyping errors is an important issue in genetic research, yet it has been relatively less studied in samples consisting of unrelated individuals. In this article, we consider several models of genotyping errors, which were originally proposed for pedigree data, for unrelated population samples with single nucleotide polymorphism (SNP) genotype data. The mathematical con...

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ژورنال

عنوان ژورنال: Human Heredity

سال: 2008

ISSN: 0001-5652,1423-0062

DOI: 10.1159/000181153